A necessary hero

نویسنده

  • Henry R. Bourne
چکیده

How will we know when it’s done? Today’s computational methods can generate reasonable homology models with a minimum of 30% sequence identity within a family. Once a genome is completed and subdivided into families that are 30% identical, it is easy to calculate how many structure determinations are necessary to yield models for that genome. Our accountants, the bioinformaticists, estimate we will need 10,000 new structure determinations to model the whole protein universe.

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عنوان ژورنال:
  • Current Biology

دوره 9  شماره 

صفحات  -

تاریخ انتشار 1999